Recombinant IGFBP3 Monoclonal Antibody

• Background:

  Insulin-like growth factor-binding protein 3 (IGFBP3) is a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Laron Syndrome.

• Abbreviation:

  IGFBP3

• UniProt:

  P17936

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant human IGFBP3 fragment

• Target:

  IGF-binding protein; Insulin-like Growth Factor Binding Protein; IBP; IGFBP3; BP-53; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; IGF-; Insulin-like Growth Factor Binding Protein 3

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A496

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cell Biology; Signal Transduction; Cardiovascular; Metabolism; Cancer

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  32 kDa

• Observed Molecular Weight:

  26, 43 kDa

• Isotype:

  IgG, κ