Recombinant AKR1B1 Monoclonal Antibody

• Background:

  This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 37 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

• Abbreviation:

  AKR1B1

• UniProt:

  P15121

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human AKR1B1 protein

• Target:

  ALR; MGC; ALDR; AKR1B; AKR1B1; ADR; ALDR1; ALR2; AR; MGC1804; AKR1B 1; Aldehyde reductase; Aldehyde reductase 1; Aldo keto reductase family 1; aldo-keto reductase family 1; Aldo-keto reductase family 1 member B1; Aldose reductase; aldr 1; Lii5 2 CTCL tumor antigen; Lii5-2 CTCL tumor antigen|aldehyde reductase 1|aldo-keto reductase family 1; Low Km aldose reductase; member B1; member B1 (aldose reductase) ; member B1|aldose reductase|low Km aldose reductase

• Clonality:

  Monoclonal

• Clone:

  9D9

• Conjugation:

  Unconjugated

• Applications:

  WB; ICC/IF; IP

• Field of Research:

  Signal Transduction; Metabolism

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000; ICC/IF 1:20-1:100; IP 0.2-1 μL/mg of lysate

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  35 kDa

• Observed Molecular Weight:

  37 kDa

• Isotype:

  IgG