Recombinant LILRB1 Monoclonal Antibody

• Background:

  LILRB1 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. This protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) . The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.

• Abbreviation:

  LILRB1

• UniProt:

  Q8NHL6

• Host:

  Rabbit

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Recombinant human LILRB1 fragment

• Target:

  LILRB; ILT; LIR; MIR; LILRB1; CD85J; ILT-2; ILT2; LIR-1; LIR1; MIR-7; MIR7; PIR-B; PIRB; ILT2; LILRB1; CD85; CD85 antigen; CD85 antigen like family member J; CD85 antigen-like family member J; CD85j antigen; Ig like transcript 2; ILT 2; immunoglobulin like transcript 2; Immunoglobulin-like transcript 2; leukocyte Ig like receptor 1; leukocyte immunoglobulin like receptor; Leukocyte immunoglobulin like receptor 1; leukocyte immunoglobulin like receptor subfamily B member 1; Leukocyte immunoglobulin like receptor subfamily B member 1 precursor; leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform; leukocyte immunoglobulin-like receptor; Leukocyte immunoglobulin-like receptor 1; Leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform; LIR 1; LIRB1; member 1; MIR 7; Monocyte/macrophage immunoglobulin like receptor 7; Monocyte/macrophage immunoglobulin-like receptor 7; PIR B; subfamily B; subfamily B (with TM and ITIM domains)

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A481

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC; IF; FCM

• Field of Research:

  Immunology

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:100-1:500; IF 1:50; FCM 1:50-1:100

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  71 kDa

• Observed Molecular Weight:

  115, 19 kDa

• Isotype:

  IgG, κ