Recombinant Human Leukocyte Ig-Like Receptor B1/ LILRB1/ILT2/CD85j (C-6His-Avi) Biotinylated

• Background:

  The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR) ) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR) . Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes, dendritic cells, and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.

• Abbreviation:

  LILRB1; ILT2; CD85j

• Synonyms:

  CD85 Antigen-Like Family Member J; CD85j; ILT-2; ILT2; Immunoglobulin-Like Transcript 2; LILRB1; LIR-1; Leukocyte Immunoglobulin-Like Receptor 1; Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1; MIR-7; Monocyte/Macrophage Immunoglobulin-Like Receptor 7

• UniProt:

  D9IDM8

• Accession Number:

  D9IDM8

• Expression System:

  HEK293 Cells

• Conjugation:

  Biotinylated

• Tag:

  C-His-Avi

• Sequence:

  Gly24-His458

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  50.0 kDa

• Observed Molecular Weight:

  70-90 kDa

• Species:

  Human