Recombinant HMGA1 Monoclonal Antibody

• Background:

  HMGA1 a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. HMGA1 preferentially binds to the minor groove of AT-rich regions in double-stranded DNA.

• Abbreviation:

  HMGA1

• UniProt:

  P17096

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Recombinant human HMGA1 fragment

• Target:

  HMGA; HMGA1; HMG-R; HMGA1A; HMGIY; High mobility group (nonhistone chromosomal) protein isoforms I and Y; High mobility group AT hook 1; High mobility group AT-hook protein 1; High mobility group protein 1; High mobility group protein A1; High mobility group protein HMG-I/HMG-Y; High mobility group protein Ia; High mobility group protein R; HMG R; HMG-I (Y) ; MGC12816; MGC4242; MGC4854; Nonhistone chromosomal high mobility group protein HMG I/HMG Y

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A442

• Conjugation:

  Unconjugated

• Applications:

  IHC; IF; WB

• Field of Research:

  Microbiology; Epigenetics and Nuclear Signaling; Cancer

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:100-1:1000; IF 1:50

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  12 kDa

• Observed Molecular Weight:

  16 kDa

• Isotype:

  IgG, κ