Recombinant VPAC2 Monoclonal Antibody

• Background:

  Human VIPR2 (Vasoactive Intestinal Polypeptide Receptor 2), also known as VPAC2, is a 60-70 kDa seven transmembrane glycoprotein receptor, which belongs to the G protein-coupled receptor 2 family of proteins. In its first extracellular region hormone receptor domain (aa 49-114) contains a mature chain, which has three N-linked glycosylation sites and a "Cilia targeting signal", which is composed of and Arg -Composition of Asp-Tyr-Arg sequence. Human VIPR2 has relatively high homology with mouse and rat VIPR2. VIPR2 is mainly expressed in skeletal muscle, CD4+ T cells, smooth muscle cells, dendritic cells, liver precursor cells, single cells, synthetic cells and selective neurons. VIPR2 couples with CAMP-mediated signal transduction pathways, and binds VIP and pituitary adenase activating polypeptide (PACAP) .

• Abbreviation:

  VPAC2

• UniProt:

  P41587

• Host:

  Rabbit

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Recombinant human VPAC2 fragment

• Target:

  VIPR; VIP2R; VIPR2

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A391

• Conjugation:

  Unconjugated

• Applications:

  IHC; IF

• Field of Research:

  Neuroscience; Tags & Cell Markers; Signal Transduction; Cancer; Cardiovascular

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:200-1:500; IF 1:50

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG, κ