Recombinant Histone H1 (CT) Monoclonal Antibody

• Background:

  Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.

• Abbreviation:

  Histone H1

• UniProt:

  P10412

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide corresponding to the C-terminus of human histone H1.4 protein

• Target:

  H1F; H1s; H1-; dJ221C; H1.4; H1E; H1F4; H1s-4; dJ221C16.5; RMNS; HIST1H1E; H1-4; dJ221C16.5; H1.4; H1F4; H1s-4; HIST1H1E; RMNS

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A247

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC; IF; FCM

• Field of Research:

  Epigenetics and Nuclear Signaling

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000; IHC 1:50-1:200; IF 1:50; FCM 1:50-1:100

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  30 kDa

• Observed Molecular Weight:

  30 kDa

• Isotype:

  IgG, κ