Recombinant ASGR1 Monoclonal Antibody

• Background:

  Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.Calcium is required for ligand binding.

• Abbreviation:

  ASGR1

• UniProt:

  P07306

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant human ASGR1 fragment

• Target:

  ASGR; C type lectin domain family 4 member H; CLEC4H; ASGP-R; ASGR1; ASGPR; ASGPR1; CLEC4H1; HL-1; ASGPR 1; ASGP-R 1; Asialoglycoprotein receptor 1; C type lectin domain family 4 member H1; C-type lectin domain family 4 member H1; Hepatic lectin H1

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A134

• Conjugation:

  Unconjugated

• Applications:

  FCM; IP; WB; IHC; IF

• Field of Research:

  Signal Transduction; Tags & Cell Markers

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50; FCM 1:50-1:100; IP 1:50-1:100

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  33 kDa

• Observed Molecular Weight:

  40-50 kDa

• Isotype:

  IgG, κ