Recombinant Human ASGR1/ASGPR1 Protein (His Tag)

• Background:

  Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor; belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits; ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins; recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1; results in the complex is internalized and transported to a sorting organelle; then ASGPR1 and ligand can be disassociated; ASGPR1 returns to the cell membrane surface.

• Abbreviation:

  ASGR1; ASGPR1

• Synonyms:

  ASGP-R 1; ASGPR 1; ASGR1; Asialoglycoprotein Receptor 1; C-Type Lectin Domain Family 4 Member H1; CLEC4H1; HL-1; Hepatic Lectin H1

• UniProt:

  P07306

• Accession Number:

  P07306

• Expression System:

  HEK293 Cells

• Tag:

  C-His

• Sequence:

  Gln62-Ile291

• Field of Research:

  Signal Transduction; Tags & Cell Markers

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  27.4 kDa

• Observed Molecular Weight:

  34-48 kDa

• Species:

  Human