Recombinant CD117/c-Kit Monoclonal Antibody

• Background:

  This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  CD117

• UniProt:

  P10721

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Recombinant Human CD117/c-Kit protein

• Target:

  KIT; C-Kit; CD117; PBT; SCFR; Mast/stem cell growth factor receptor Kit; p145 c-kit; Piebald trait protein; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; SCFR; C Kit; CD_antigen: CD117; c-Kit Ligand; Kit Ligand; KIT oncogene; KIT proto oncogene receptor tyrosine kinase; KIT proto-oncogene receptor tyrosine kinase; Mast cell growth factor receptor; MGF; Proto oncogene c Kit; Proto oncogene tyrosine protein kinase Kit; SCF Receptor; soluble KIT variant 1; Steel Factor Receptor; Stem cell factor receptor; tyrosine protein kinase Kit; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein; c Kit/CD117; c-Kit

• Clonality:

  Monoclonal, Recombinant

• Clone:

  7C3

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Immunology; Tags & Cell Markers; Signal Transduction; Neuroscience; Stem Cells; Cancer; Developmental Biology

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  110 kDa

• Observed Molecular Weight:

  130 kDa

• Isotype:

  IgG, κ