Recombinant c-Kit/CD117 Monoclonal Antibody

• Background:

  This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  KIT

• UniProt:

  P10721

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human c-Kit/CD117 protein

• Target:

  KIT; C-Kit; CD117; PBT; SCFR; Mast/stem cell growth factor receptor Kit; p145 c-kit; Piebald trait protein; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; SCFR; C Kit; CD_antigen: CD117; c-Kit Ligand; Kit Ligand; KIT oncogene; KIT proto oncogene receptor tyrosine kinase; KIT proto-oncogene receptor tyrosine kinase; Mast cell growth factor receptor; MGF; Proto oncogene c Kit; Proto oncogene tyrosine protein kinase Kit; SCF Receptor; soluble KIT variant 1; Steel Factor Receptor; Stem cell factor receptor; tyrosine protein kinase Kit; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein

• Clonality:

  Monoclonal

• Clone:

  5D9

• Conjugation:

  Unconjugated

• Applications:

  IHC-P

• Field of Research:

  Immunology; Tags & Cell Markers; Signal Transduction; Neuroscience; Stem Cells; Cancer; Developmental Biology

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  IHC-P 1:100-1:500

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Isotype:

  IgG