Recombinant ARID1A Monoclonal Antibody

• Background:

  This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation.

• Abbreviation:

  ARID1A

• UniProt:

  O14497

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human ARID1A protein

• Target:

  CSS; OSA; MRD; BAF; hOSA; C1orf; SMARCF; B120; BAF250; BAF250a; BM029; C1orf4; CSS2; ELD; MRD14; OSA1; P270; SMARCF1; hELD; hOSA1; ARID1A; BAF250; BAF250a; BM029; C1orf4; CSS2; ELD; hELD; hOSA1; MRD14; OSA1; P270; SMARCF1; actin dependent regulator of chromatin; actin-dependent regulator of chromatin subfamily F member 1; ARI1A; ARID domain containing protein 1A; ARID domain-containing protein 1A; AT rich interactive domain 1A; AT rich interactive domain 1A (SWI like) ; AT rich interactive domain containing protein 1A; AT-rich interactive domain-containing protein 1A; brain protein 120; BRG1 associated factor 250; BRG1 associated factor 250a; BRG1-associated factor 250; BRG1-associated factor 250a; chromatin remodeling factor p250; chromosome 1 open reading frame 4; matrix associated; matrix-associated; member 1; Osa homolog 1; OSA1 nuclear protein; subfamily f; SWI like protein; SWI SNF complex protein p270; SWI/SNF complex protein p270; SWI/SNF related; SWI/SNF-related; SWI-like protein; ARID1A

• Clonality:

  Monoclonal, Recombinant

• Clone:

  5H13

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Signal Transduction; Epigenetics and Nuclear Signaling; Cancer

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:200-1:1000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG, κ