Recombinant vWF Monoclonal Antibody

• Background:

  Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.

• Abbreviation:

  VWF

• UniProt:

  P04275

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human vWF protein

• Target:

  Von Willebrand antigen; VWF; F8VWF; VWD; Coagulation factor VIII; Coagulation factor VIII VWF; Factor VIII related antigen; von Willebrand antigen 2; von Willebrand antigen II; Von Willebrand disease; Von Willebrand Factor

• Clonality:

  Monoclonal

• Clone:

  11G9

• Conjugation:

  Unconjugated

• Applications:

  IHC-P

• Field of Research:

  Cardiovascular; Cancer; Stem Cells

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  IHC-P 1:500-1:2000

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Isotype:

  IgG