Recombinant RSK3 Monoclonal Antibody

• Background:

  ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues., Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB., PTM:Autophosphorylated on Ser-377, as part of the activation process., similarity:Belongs to the protein kinase superfamily., similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 2 protein kinase domains., subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation., tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle.

• Abbreviation:

  RSK3

• UniProt:

  Q15349

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human RSK3 protein

• Target:

  RPS6KA; p90RSK; p90-RSK; pp90RSK; RPS6KA2; HU-2; MAPKAPK1C; RSK; RSK3; S6K-alpha; S6K-alpha2; p90-RSK3; p90RSK2; pp90RSK3;90 kDa ribosomal protein S6 kinase 2;90kDa; HU 2; KS6A2; MAP kinase activated protein kinase 1c; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Mitogen.activated protein kinase-activated protein kinase 1C; p90 RSK3; p90-RSK 2; polypeptide 2; ribosomal protein S6 kinase; Ribosomal protein S6 kinase alpha-2; Ribosomal S6 kinase 3; RSK 3; RSK-3; S6K alpha; S6K alpha 2; S6K-alpha-2; RSK3

• Clonality:

  Monoclonal, Recombinant

• Clone:

  2D5

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Epigenetics and Nuclear Signaling; Signal Transduction

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:200-1:1000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG, κ