Recombinant Hsp70 Monoclonal Antibody

• Background:

  This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

• Abbreviation:

  HSP70

• UniProt:

  P0DMV8; P0DMV9

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human Hsp70 protein

• Target:

  HSX; HSPA; HEL-S; HSP; HEL-S-103; HSP70-1; HSP70-1A; HSP70.1; HSP70I; HSP72; HSPA1; heat shock protein family A (Hsp70) member 1A; heat shock protein family A (Hsp70) member 1B; HSP70.2; HSP70-1B; HSP70-2; HSPA1A; Hsp70; Heat shock 70 kDa protein 1A; HSX70; heat shock protein family A (Hsp70) member 1B; HSP70.1; HSP70.2; HSP70-1; HSP70-1A; HSP70-1B; HSP70-2; HSP70I; HSP72; HSPA1

• Clonality:

  Monoclonal, Recombinant

• Clone:

  8D3

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Signal Transduction; Cancer

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:400-1000; WB 1:1000-5000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  70 kDa

• Observed Molecular Weight:

  70 kDa

• Isotype:

  IgG, κ