Recombinant VEGF Receptor 1 Monoclonal Antibody

• Background:

  FLT1 (fms related tyrosine kinase 1) Homo sapiens This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig) -like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

• Abbreviation:

  VEGF Receptor 1

• UniProt:

  P17948

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human VEGF Receptor 1 protein

• Target:

  Fms-like tyrosine kinase; Fms-related tyrosine kinase; Vascular endothelial growth factor receptor; Svegfr; FLT; FLT-1; VEGFR-1; VEGFR1; FLT1; Fms-related tyrosine kinase 1; Svegfr-1; FRT; Vascular endothelial growth factor receptor 1; Fms-like tyrosine kinase 1; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; Vascular permeability factor receptor; FLT-1; Fms-related tyrosine kinase 10; VEGFR-1; EC 2.7.10.1; FLT 1; Fms like tyrosine kinase 1; Fms related tyrosine kinase 1; Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) ; Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor; Soluble VEGF receptor 1 14; Soluble VEGFR1 variant 2; Soluble VEGFR1 variant 21; Tyrosine protein kinase FRT; Tyrosine protein kinase receptor FLT; Vascular endothelial growth factor vascular permeability factor receptor; Vascular permeability factor receptor 1; VEGFR 1; VEGFR1; VGFR1; FLT1

• Clonality:

  Monoclonal, Recombinant

• Clone:

  1A8

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cardiovascular; Signal Transduction; Cancer; Metabolism

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:200-1:1000; WB 1:1000-1:5000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  151 kDa

• Observed Molecular Weight:

  180 kDa

• Isotype:

  IgG, κ