Recombinant Phospho-VEGF Receptor 2 (Tyr1175) Monoclonal Antibody

• Background:

  Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

• Abbreviation:

  KDR

• UniProt:

  P35968

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide corresponding to the residues around Tyr1175 of Human Phospho-VEGF Receptor 2

• Target:

  Krd; VEGF Receptor; Fetal liver kinase; Protein-tyrosine kinase receptor flk; Vascular endothelial growth factor receptor; sVEGFR; VEGF R;6130401C; FLK; CD309; FLK1; VEGFR; VEGFR2; VEGF Receptor 2; KDR;6130401C07; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; Krd-1; Ly73; Protein-tyrosine kinase receptor flk-1; sVEGFR-2; Vascular endothelial growth factor receptor 2; VEGF R2; VEGFR-2; KDR

• Clonality:

  Monoclonal

• Clone:

  11G9

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cardiovascular; Microbiology; Signal Transduction; Stem Cells; Cancer; Metabolism

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-1:10000

• Buffer:

  10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  152 kDa

• Observed Molecular Weight:

  280 kDa

• Isotype:

  IgG