Recombinant c-Jun Monoclonal Antibody

• Background:

  Transcription factor that recognizes and binds toThe enhancer heptamer motif 5'-TGA[CG]TCA-3'., PTM:Phosphorylation enhancesThe transcriptional activity. Phosphorylated by PRKDC., similarity:Belongs toThe bZIP family., similarity:Belongs toThe bZIP family. Jun subfamily., similarity:Contains 1 bZIP domain., subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity) . Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibitsThe binding of active AP1 to its target DNA.

• Abbreviation:

  C-JUN

• UniProt:

  P05412

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human c-Jun protein

• Target:

  AP-1; AP1; c-Jun; JUN; c; Activator protein 1; AP 1; AP-1 transcription factor subunit; cJun; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; Jun oncogene; JUN protein; Jun proto oncogene; Jun proto-oncogene; JUNC; Oncogene JUN; p39; Proto oncogene c jun; Proto oncogene cJun; Proto-oncogene c-jun; Transcription Factor AP 1; Transcription Factor AP1; Transcription factor AP-1; V jun avian sarcoma virus 17 oncogene homolog; V jun sarcoma virus 17 oncogene homolog; V jun sarcoma virus 17 oncogene homolog (avian) ; vJun Avian Sarcoma Virus 17 Oncogene Homolog; V-jun avian sarcoma virus 17 oncogene homolog

• Clonality:

  Monoclonal, Recombinant

• Clone:

  5C10

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Epigenetics and Nuclear Signaling; Signal Transduction; Cancer; Immunology; Kits; Lysates; Other; Cardiovascular

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:200-1:1000; WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  36 kDa

• Observed Molecular Weight:

  43 kDa

• Isotype:

  IgG, κ