Recombinant Src Monoclonal Antibody

• Background:

  This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

• Abbreviation:

  Src

• UniProt:

  P12931

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human Src protein

• Target:

  THC; ASV; SRC1; THC6; c-SRC; p60-Src; SRC; pp60c-src; Proto-oncogene c-Src; Proto-oncogene tyrosine-protein kinase Src; Avian sarcoma virus; c SRC; CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA; cSrc; EC 2.7.10.2; Neuronal CSRC tyrosine specific protein kinase; Neuronal SRC; Oncogene SRC; OTTHUMP00000174476; OTTHUMP00000174477; p60 Src; p60Src; pp60c src; pp60csrc; Proto oncogene tyrosine protein kinase Src; Protooncogene SRC; Protooncogene SRC Rous sarcoma; SRC Oncogene; SRC proto oncogene non receptor tyrosine kinase; Tyrosine kinase pp60c src; Tyrosine protein kinase SRC 1; Tyrosine protein kinase SRC1; v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog; V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) ; v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian; c-Src

• Clonality:

  Monoclonal, Recombinant

• Clone:

  4B3

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Signal Transduction; Epigenetics and Nuclear Signaling; Cancer

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  60 kDa

• Observed Molecular Weight:

  60 kDa

• Isotype:

  IgG, κ