Recombinant TRAF6 Monoclonal Antibody

• Background:

  TNF receptor associated factor 6 (TRAF6) Homo sapiens The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines.

• Abbreviation:

  TRAF6

• UniProt:

  Q9Y4K3

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human TRAF6 protein

• Target:

  RNF; MGC; TRAF; TRAF6; MGC:3310; RNF85; E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase TRAF6; Interleukin 1 signal transducer; Interleukin-1 signal transducer; MGC 3310; MGC3310; OTTHUMP00000232772; OTTHUMP00000232773; RING finger protein 85; RNF 85; TNF receptor associated factor 6; TNF receptor-associated factor 6; TRAF 6

• Clonality:

  Monoclonal, Recombinant

• Clone:

  5A2

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cell Biology; Signal Transduction; Cancer; Immunology

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  60 kDa

• Observed Molecular Weight:

  60 kDa

• Isotype:

  IgG, κ