IRF6 Monoclonal Antibody

• Background:

  This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

• Abbreviation:

  IRF6

• UniProt:

  O14896

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide corresponding to the C-terminus of the human IRF6

• Target:

  IRF; OFC; IRF6; LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1

• Clonality:

  Monoclonal

• Clone:

  2B12

• Conjugation:

  Unconjugated

• Applications:

  ICC/IF

• Field of Research:

  Immunology; Epigenetics and Nuclear Signaling; Stem Cells

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  ICC/IF 1:20-1:100

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Isotype:

  IgG3