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IL-24 Recombinant Protein

CAT: 0223-40-600-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0223-40-600-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
NCBI Gene ID
11009
Swiss Prot
Q13007
Accession Number
NP_001172085.1
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Cancer, Immunology
Purity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized IL-24 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-24 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-24 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Interleukin 24
NCBI Organism
Homo sapiens
Other Product Names
C49A, FISP, MDA7, MOB5, ST16, IL10B, Interleukin-24, Melanoma differentiation-associated gene 7 protein, IL-24
Species
Human
Protein ID
297632401
Physical Properties
Lyophilized

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