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IL-23 Recombinant Protein

CAT: 0223-40-559-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0223-40-559-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-23 is a proinflammatory heterodimeric protein composed of two subunits, a unique p19 subunit and a p40 subunit, which is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages, and signals though a receptor comprised of IL-23R complexed with IL-12Rβ1. IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the production of IFN-gamma in NK cells, induces IL-17 production, and drives Th17 mediated responses. Recombinant IL-23 is a 53.5 kDa heterodimeric protein consisting of two subunits, p19 (170 amino acids) and p40 (306 amino acids) .*Manufactured using BTI-Tn-5B1-4 cells under license from the Boyce Thompson Institute for Plant Research, Inc.
NCBI Gene ID
51561
Swiss Prot
Q9NPF7
Accession Number
NP_057668.1
Type
Recombinant Proteins
Source
(BTI-Tn-5B1-4) High-5 Insect cells
Field of Research
Cancer, Chemokines & Cytokines, Immunology, Innate Immunity, Neuroscience
Purity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized IL-23 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-23 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-23 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Interleukin 23, alpha subunit p19
NCBI Organism
Homo sapiens
Other Product Names
P19, SGRF, IL-23, IL-23A, IL23P19, UNQ2498/PRO5798, Interleukin-23 subunit alpha, Interleukin-23 subunit p19, IL-23 subunit alpha
Species
Human
Protein ID
7706702
Physical Properties
Lyophilized

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