E-Selectin Recombinant Protein

CAT: 0223-40-553-01Size: 0.01 mgDry Ice: NoHazardous: No
CAT#:0223-40-553-01Size:0.01 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Selectins are a family of calcium-dependent type 1 transmembrane proteins. Endothelial (E) -selectin is a heavily glycosylated transmembrane protein expressed by activated endothelial cells in microvascular linings. E-selectin, along with P-selectin and L-selectin, initiate recruitment of circulating leukocytes from blood to sites of inflammation in the vascular lining through interaction with specific cell surface associated carbohydrate determinants. E-selectin consists of an N-terminal type 1 lectin domain, an EGF-like domain, 6 sushi (CCP/SCR) domains, a transmembrane sequence, and a short cytoplasmic domain. Recombinant human E-selectin is a 58.6 kDa protein containing 535 amino acid residues, corresponding to the extracellular portion of the full length protein. Due to glycosylation, E-selectin migrates at an apparent molecular weight of approximately 65-85 kDa by SDS-PAGE analysis under reducing conditions.
NCBI Gene ID
28
Swiss Prot
P16442
Accession Number
NP_065202.2
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Other
Purity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized E-Selectin recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted E-Selectin stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing E-Selectin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
NCBI Organism
Homo sapiens
Other Product Names
GTB, NAGAT, A3GALNT, A3GALT1, Histo-blood group ABO system transferase, Fucosylglycoprotein 3-alpha-galactosyltransferase, A transferase
Species
Human
Protein ID
58331216
Physical Properties
Lyophilized

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