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IL-13 Recombinant Protein

CAT: 0223-40-421-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0223-40-421-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.
NCBI Gene ID
16163
Swiss Prot
P20109
Accession Number
NP_032381.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Chemokines & Cytokines, Immunology
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized IL-13 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-13 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-13 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Interleukin 13
NCBI Organism
Mus musculus
Other Product Names
Il-13, Il-13, Interleukin-13, T-cell activation protein P600, IL-13
Species
Murine
Protein ID
6680403
Physical Properties
Lyophilized

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