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IL-13 Antibody

CAT: 0223-38-344Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-38-344Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1b, TNF-a, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. Recombinant Rat IL-13 a 12.3 kDa protein consisting of 113 amino acid residues.
CAS Number
9007-83-4
NCBI Gene ID
116553
Swiss Prot
P42203
Accession Number
P42203
Host
Rabbit
Reactivity
Rat
Immunogen
Produced from sera of rabbits immunized with highly pure recombinant Rat IL-13. Anti-Rat IL-13 specific antibody was purified by affinity chromatography employing an immobilized Rat IL-13 matrix.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Antibody Pairs
Field of Research
COVID-19, Infectious Disease, Cancer, Stem Cell, Immunology
Purification
IL-13 specific antibody was purified by affinity chromatography employing an immobilized Rat IL-13 matrix
Concentration
Batch dependent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Symbol
Il13
NCBI Official Name
Interleukin 13
NCBI Organism
Rattus norvegicus
Other Product Names
NC300 (Human), P600 (Murine)
Tested Applications
ELISA, WB
Protein ID
P42203.1
Physical Properties
Lyophilized

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