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TACI Recombinant Protein

CAT: 0223-40-308-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0223-40-308-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TACI, a member of the TNF Receptor superfamily, is expressed in the small intestine, spleen, thymus, peripheral blood leukocytes, activated T cells, and resting B cells. TACI binds to both APRIL and BAFF and can stimulate the activation of transcription factors; NF-kappaB, AP-1, and mediates calcineurin dependent activation of NF-AT (nuclear-factor of activated T cells) . TACI also plays a key role in the stimulation of B and T cell function. Soluble TACI inhibits APRIL-stimulated proliferation of primary B-cells by blocking the binding of APRIL to the membrane anchored TACI receptor. Recombinant human TACI is a soluble 160 amino acid polypeptide (17.8 kDa) comprising the TNFR homologous cysteine rich extracellular domain of the TACI protein.
NCBI Gene ID
23495
Swiss Prot
O14836
Accession Number
NP_036584.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Immunology
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized TACI recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TACI is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TACI recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 13B
NCBI Organism
Homo sapiens
Other Product Names
CVID, RYZN, TACI, CD267, CVID2, TNFRSF14B, Tumor necrosis factor receptor superfamily member 13B, Transmembrane activator and CAML interactor
Species
Human
Protein ID
6912694
Physical Properties
Lyophilized

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