Products for Research Use Only

TRAIL Recombinant Protein

CAT: 0223-40-297-01Size: 0.01 mgDry Ice: NoHazardous: No
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CAT#:0223-40-297-01Size:0.01 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TRAIL/Apo2L is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain", which activates the cell's apoptotic machinery. Recombinant human soluble TRAIL/Apo2L is a 168 amino acid polypeptide (19.6 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL/Apo2L protein.
NCBI Gene ID
8743
Swiss Prot
P50591
Accession Number
NP_001177871.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Cancer, Growth Factors, Immunology
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized TRAIL recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TRAIL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TRAIL recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Tumor necrosis factor (ligand) superfamily, member 10
NCBI Organism
Homo sapiens
Other Product Names
TL2, APO2L, CD253, TRAIL, Apo-2L, Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand
Species
Human
Protein ID
300193032
Physical Properties
Lyophilized