TRAIL-R1 Recombinant Protein

• Background:

  TRAIL-R1 (DR4; CD261) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

• NCBI Gene ID:

  8797

• Swiss Prot:

  Q62009

• Accession Number:

  O00220

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Apoptosis, Cancer, Homeostasis, Immunology, Signal Transduction

• Concentration:

  1mg/ml after reconstitution.

• Buffer:

  Contains PBS. Reconstitute with 50 μ l sterile water.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Tumor necrosis factor receptor superfamily, member 10a

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DR4, TNFRSF 10A, APO2, CD261, TRAIL Receptor 1, TNF-related Apoptosis-inducing Ligand Receptor 1

• Species:

  Human, Mouse

• Protein ID:

  1945072

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3