IL-31 Recombinant Protein

• Background:

  Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor) . GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant IL-31 is a 15.8 kDa protein containing 141 amino acid residues.

• NCBI Gene ID:

  386653

• Swiss Prot:

  Q6EBC2

• Accession Number:

  NP_001014358.1

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Chemokines & Cytokines, Immunology, Signal Transduction

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized IL-31 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-31 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-31 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Interleukin 31

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  IL-31, Interleukin-31, IL-31

• Species:

  Human

• Protein ID:

  62122911

• Physical Properties:

  Lyophilized