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IL-31 Recombinant Protein

CAT: 0223-40-272-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0223-40-272-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor) . GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant IL-31 is a 15.8 kDa protein containing 141 amino acid residues.
NCBI Gene ID
386653
Swiss Prot
Q6EBC2
Accession Number
NP_001014358.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Chemokines & Cytokines, Immunology, Signal Transduction
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized IL-31 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-31 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-31 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Interleukin 31
NCBI Organism
Homo sapiens
Other Product Names
IL-31, Interleukin-31, IL-31
Species
Human
Protein ID
62122911
Physical Properties
Lyophilized

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