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FGF-23 Recombinant Protein

CAT: 0223-40-194-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0223-40-194-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Recombinant human FGF-23 is a 22.5 kDa globular protein containing 228 amino acid residues.
NCBI Gene ID
8074
Swiss Prot
Q9GZV9
Accession Number
NP_065689.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Obesity
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized FGF-23 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted FGF-23 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing FGF-23 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Fibroblast growth factor 23
NCBI Organism
Homo sapiens
Other Product Names
ADHR, FGFN, HYPF, HPDR2, PHPTC, UNQ3027/PRO9828, Fibroblast growth factor 23, Phosphatonin, FGF-23
Species
Human
Protein ID
10190674
Physical Properties
Lyophilized

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