IL-1 beta Recombinant Protein

• Background:

  IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant murine IL-1β is a 17.5 kDa protein containing 153 amino acid residues.

• NCBI Gene ID:

  16176

• Swiss Prot:

  P10749

• Accession Number:

  NP_032387.1

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Chemokines & Cytokines, Immunology, Inflammasomes

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized IL-1 beta recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-1 beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-1 beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Interleukin 1 beta

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Il-1b, IL-1beta, Interleukin-1 beta, IL-1 beta

• Species:

  Murine

• Protein ID:

  6680415

• Physical Properties:

  Lyophilized