IP-10 Antibody

• Background:

  Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.

• NCBI Gene ID:

  15945

• Swiss Prot:

  P17515

• Accession Number:

  P17515

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mIP-10 (murine IP-10) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Functional Antibodies, Antibody Pairs

• Field of Research:

  Chemokines & Cytokines

• Purification:

  Anti-mIP-10 specific antibody was purified by affinity chromatography employing immobilized mIP-10 matrix.

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  IP-10 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol:

  Cxcl10

• NCBI Official Name:

  Chemokine (C-X-C motif) ligand 10

• NCBI Organism:

  Mus musculus

• Other Product Names:

  C7, IP10, CRG-2, INP10, IP-10, Ifi10, mob-1, Scyb10, gIP-10, Crg2, Inp10, C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10

• Tested Applications:

  ELISA, WB, Neutralization Assay

• Protein ID:

  124494

• Physical Properties:

  Lyophilized