CD79b Antibody [CB3-1]

• Background:

  CD79 is a disulfide-linked heterodimer composed of an alpha chain (CD79a) and a beta chain (CD79b) that associates non-covalently with membrane immunoglobulin to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. Crosslinking of the BCR leads to B cell activation. The monoclonal antibody CB3-1 reacts with the beta chain of CD79.

• NCBI Gene ID:

  974

• Swiss Prot:

  P40259

• Accession Number:

  P40259

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Ramos B cells

• Clonality:

  Monoclonal

• Clone:

  [CB3-1]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Concentration:

  0.1 mg/mL

• Buffer:

  Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG1

• Specificity:

  CD79b

• Applications Notes:

  CD79b Antibody [CB3-1] for use in flow cytometry, western blotting, and immunoprecipitation assays.

• Symbol:

  CD79B

• NCBI Official Name:

  B-cell antigen receptor complex-associated protein beta chain

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  B29, Igbeta

• Tested Applications:

  Flow, Blocking, Costimulation, Stimulation

• Physical Properties:

  Liquid