CD79B Antibody

• Background:

  The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig) . Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.

• NCBI Gene ID:

  974

• Swiss Prot:

  P40259

• Accession Number:

  P40259

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CD79B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-121 amino acids from the Central region of human CD79B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CD79B

• NCBI Official Name:

  B-cell antigen receptor complex-associated protein beta chain

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 03:

  Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)

• Background Reference 04:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Other Product Names:

  B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b, CD79B, B29, IGB

• Tested Applications:

  WB

• Protein ID:

  728994

• Physical Properties:

  Liquid