CD33 Antibody [WM53] (PE)

• Background:

  CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.

• NCBI Gene ID:

  945

• Swiss Prot:

  P20138

• Accession Number:

  P20138

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Clone:

  [WM53]

• Conjugation:

  PE

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Stem Cell

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS/NaN3 and a stabilizing agent

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG1

• Specificity:

  CD33

• Applications Notes:

  CD33 Antibody [WM53] for use in flow cytometry assays.

• Symbol:

  CD33

• NCBI Official Name:

  CD33 molecule

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Gp67, p67, Siglec-3

• Tested Applications:

  Flow

• Physical Properties:

  Liquid