CD33 Antibody [WM53] (FITC)

• Background:

  The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67. CD33 is expressed on monocytes, granulocytes, dendritic cells, mast cells, and myeloid progenitors to the exclusion of hematopoietic stem cells, lymphocytes, and platelets. It functions to assist sialic acid-dependent cell adhesion.

• NCBI Gene ID:

  945

• Swiss Prot:

  P20138

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Clone:

  WM53

• Conjugation:

  FITC

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Mouse IgG1, kappa

• Specificity:

  The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67.

• Symbol:

  CD33

• NCBI Official Name:

  CD33 molecule

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

• Background Reference 02:

  Favaloro, E. J., Bradstock, K. F., Kabral, A., Grimsley, P., Zowtyj, H., Zola, H. (1988) . Further characterization of human myeloid antigens (gp160, 95; gp150; gp67) : investigation of epitopic heterogeneity and non‐haemopoietic distribution using panels of monoclonal antibodies belonging to CD‐11b, CD‐13 and CD‐33.British journal of haematology,69 (2), 163-171

• Background Reference 03:

  Freeman, S. D., Kelm, S., Barber, E. K., Crocker, P. R. (1995) . Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.Blood,85 (8), 2005-2012.

• Other Product Names:

  P67, SIGLEC3, SIGLEC-3, CD33

• Tested Applications:

  Flow

• Physical Properties:

  Liquid