RLA-DQ Antibody [2C4]

• Background:

  The monoclonal antibody 2C4 reacts with RLA-DQ-transfected cells, but not with RLA-DR-transfected cells. In normal adult rabbits, the antibody reacts with 30-60% of peripheral blood leukocytes. It has also been reported that the antibody stains lymphocytes and macrophages in the spleen, lymphocytes in the thymic medulla and some cells in the cortex, Kupffer cells in the liver, and synovial lining cells (e.g., infiltrating macrophages) in inflamed synovium. DQalpha transcripts have been detected in bone marrow and spleen and to a lesser extent in appendix, lymph nodes, and other organs.

• Host:

  Mouse

• Reactivity:

  Rabbit

• Immunogen:

  Rabbit spleen cells

• Clonality:

  Monoclonal

• Clone:

  [2C4]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG2a

• Specificity:

  RLA-DQ

• Applications Notes:

  RLA-DQ Antibody [2C4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, ELISA, and blocking assays.

• Tested Applications:

  Flow, FLISA

• Physical Properties:

  Liquid