H-2Dd Antibody [34-5-8S] (PE)

• Background:

  The monoclonal antibody 34-5-8S reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of alpha1 and alpha2 chains when complexed with beta2-microglobulin. The antibody does not react with H-2Dd alpha chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.

• NCBI Gene ID:

  14964

• Swiss Prot:

  P01899

• Accession Number:

  P01899

• Host:

  Mouse

• Reactivity:

  Mouse

• Immunogen:

  BDF1 mouse splenocytes

• Clonality:

  Monoclonal

• Clone:

  [34-5-8S]

• Conjugation:

  PE

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Concentration:

  0.1 mg/mL

• Buffer:

  Supplied in PBS/NaN3 and a stabilizing agent

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG2a

• Specificity:

  H-2Dd

• Applications Notes:

  H-2Dd Antibody [34-5-8S] for use in flow cytometry assays.

• Symbol:

  H2-D1

• NCBI Official Name:

  Histocompatibility 2, D region locus 1

• NCBI Organism:

  Mus musculus

• Other Product Names:

  MHC Class I

• Tested Applications:

  IHC-P, IHC-Fr, Flow, IP

• Physical Properties:

  Liquid