TCR beta Antibody [H57-597]

• Background:

  The alphabeta TCR is expressed on T lymphocytes of all mouse strains tested. The H57-597 monoclonal antibody does not react with gammadelta TCR-bearing cells. Plate-bound or soluble H57-597 activates alphabeta TCR-bearing T cells. In vitro and in vivo, H57-597 can induce immature thymocytes to undergo apoptosis. In vivo administration of H57-597 has been shown to deplete alphabeta TCR-bearing cells to near completion and prevent graft rejection.

• NCBI Gene ID:

  21577

• Host:

  Hamster

• Reactivity:

  Mouse

• Immunogen:

  TCR affinity purified from mouse T-cell hybridoma DO-11.10

• Clonality:

  Monoclonal

• Clone:

  [H57-597]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG

• Specificity:

  TCRbeta

• Applications Notes:

  TCR beta Antibody [H57-597] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, stimulaton, separation, and depletion assays.

• Symbol:

  Tcrb

• NCBI Official Name:

  T cell receptor beta chain

• NCBI Organism:

  Mus musculus

• Tested Applications:

  ELISA, WB, WB-NR, IHC-Fr, ICC, Flow, Blocking, IP, Adhesion

• Physical Properties:

  Liquid