TCR beta Antibody [H57-597] (FITC)

• Background:

  The H57-597 monoclonal antibody is specific for the beta chain of the mouse T cell Receptor (TCR) . The crosslinking induces activation and proliferation of T cells, as a plate-bound or a soluble H57-597, or the plate-bound antibody can induce apoptosis, based on assay conditions. The beta chain of the TCR can combine with the alpha chain of the receptor to produce the alpha-beta TCR, which is expressed by the NKT cells, by the NK1.1+ thymocytes and most of the T cells. The beta chain does not react with the gamma-delta TCR-bearing cells, expressed by a small number of T cells. This antibody can be used as a phenotypic marker for the TCR beta expressing cells or for the functional purpose of TCR-mediated cell activation or apoptosis.

• NCBI Gene ID:

  21577

• Host:

  Hamster

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Clone:

  H57-597

• Conjugation:

  FITC

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Armenian Hamster IgG

• Specificity:

  The H57-597 monoclonal antibody is specific for the beta chain of the mouse T cell Receptor (TCR) .

• Symbol:

  Tcrb

• NCBI Official Name:

  T cell receptor beta chain

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Tib, TCRbeta, Tcrb

• Tested Applications:

  Flow

• Physical Properties:

  Liquid