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CD30 Antibody [mCD30.1]

CAT: 0223-98-727Size: 0.5 mgDry Ice: NoHazardous: No
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CAT#:0223-98-727Size:0.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. Murine CD30 is expressed predominantly in the thymus and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. In anti-CD3epsilon-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-gamma production. While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.
NCBI Gene ID
21941
Swiss Prot
Q60846
Accession Number
Q60846
Host
Hamster
Reactivity
Mouse
Immunogen
Mouse CD30-mouse IgG1 fusion protein
Clonality
Monoclonal
Clone
[mCD30.1]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG
Specificity
CD30
Applications Notes
CD30 Antibody [mCD30.1] for use in flow cytometry, costimulation, stimulation, and blocking assays.
Symbol
Tnfrsf8
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 8
NCBI Organism
Mus musculus
Other Product Names
Ki-1, Ber-H2
Tested Applications
WB, Flow, IP
Physical Properties
Liquid

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