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Oct-1 Antibody

CAT: 0223-79-773Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-773Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
NCBI Gene ID
5451
Swiss Prot
P14859
Accession Number
NP_001185712.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Oct-1 antibody was raised against a peptide sequence around aa.270~274 (T-P-K-R-I) derived from Human Oct-1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
90 kDa
Specificity
This antibody detects endogenous level of total Oct-1protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
POU2F1
NCBI Official Name
POU class 2 homeobox 1
NCBI Organism
Homo sapiens
Background Reference 01
Prefontaine G. G., Walther R., Giffin W., Lemieux M. E., Pope L., Hache R. J. G. J. Biol. Chem, 274:26713-26719 (1999) Mahajan S. S., Wilson A. C. Mol. Cell. Biol. 20:919-928 (2000)
Other Product Names
OCT1, OTF1, oct-1B, 41183
Tested Applications
WB
Protein ID
311771667
Physical Properties
Liquid

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