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OCT-4 Antibody

CAT: 0223-79-645Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-645Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') . Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency
NCBI Gene ID
5460
Swiss Prot
Q01860
Accession Number
NP_002692.2
Host
Rabbit
Reactivity
Human
Immunogen
OCT-4 antibody was raised against a peptide sequence around aa.232~236 (R-K-R-T-S) derived from OCT-4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
45 kDa
Specificity
This antibody detects endogenous level of total OCT-4 protein.
Applications Notes
Western Blot: 1:1000
Symbol
POU5F1
NCBI Official Name
POU class 5 homeobox 1
NCBI Organism
This antibody was raised against a peptide sequence around aa.232~236 (R-K-R-T-S) derived from OCT-4
Background Reference 01
Pesce, M. and Scholer, H. R. (2001) Stem Cells 19, 271-278. Pan, G. and Thomson, J. A. (2007) Cell Res 17, 42-9. Cauffman, G. et al. (2006) Stem Cells 24, 2685-91.
Other Product Names
OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4, CDKN6, Otc3
Tested Applications
WB
Protein ID
42560248
Physical Properties
Liquid

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