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CCR5 (CD195) Antibody

CAT: 0223-79-765Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-765Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
NCBI Gene ID
1234
Swiss Prot
P51681
Accession Number
NP_000570.1
Host
Rabbit
Reactivity
Human
Immunogen
CCR5 (CD195) antibody was raised against a peptide sequence around aa.11~15 (D-I-N-Y-Y) derived from Human CCR5 (CD195) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
41 kDa
Specificity
This antibody detects endogenous level of total CCR5 (CD195) protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
CCR5
NCBI Official Name
Chemokine (C-C motif) receptor 5 (gene/pseudogene)
NCBI Organism
Homo sapiens
Background Reference 01
Samson M., Labbe O., Mollereau C., Vassart G., Parmentier M. Biochemistry 35:3362-3367 (1996) Raport C. J., Gosling J., Schweichart V. L., Gray P. W., Charo I. F. J. Biol. Chem. 271:17161-17166 (1996) Combadiere C., Ahuja S. K., Tiffany H. L., Murphy P. M. J. Leukoc. Biol. 60:147-152 (1996)
Other Product Names
CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, CREB2, CREBP1, CKR5
Tested Applications
WB
Protein ID
4502639
Physical Properties
Liquid

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