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Adiponectin Antibody

CAT: 0223-79-764Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-764Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-κ -B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
NCBI Gene ID
9370
Swiss Prot
Q15848
Accession Number
NP_001171271.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Adiponectin antibody was raised against a peptide sequence around aa.235~239 (T-G-F-L-L) derived from Human Adiponectin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
27 kDa
Specificity
This antibody detects endogenous level of total Adiponectin protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
ADIPOQ
NCBI Official Name
Adiponectin, C1Q and collagen domain containing
NCBI Organism
Homo sapiens
Background Reference 01
Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., Mori Y., Ide T., Murakami K., Yoda M. Kadowaki T. Nat. Med. 7:941-946 (2001) Richards A. A., Stephens T., Charlton H. K., Jones A., Macdonald G. A., Prins J. B., Whitehead J. P. Mol. Endocrinol. 20:1673-1687 (2006)
Other Product Names
ACDC, ADPN, APM1, APM-1, GBP28, ACRP30, ADIPQTL1, ACDC
Tested Applications
WB
Protein ID
295317372
Physical Properties
Liquid

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