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E2F2 Antibody

CAT: 0223-79-756Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-756Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.
NCBI Gene ID
1870
Swiss Prot
Q14209
Accession Number
NP_004082.1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E2F-2 antibody was raised against a peptide sequence around aa.425~429 (L-F-D-S-Y) derived from Human E2F-2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
45 kDa
Specificity
This antibody detects endogenous level of total E2F-2 protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
E2F2
NCBI Official Name
E2F transcription factor 2
NCBI Organism
Homo sapiens
Background Reference 01
Rubin S. M., Gall A. -L., Zheng N., Pavletich N. P. Cell 123:1093-1106 (2005)
Other Product Names
E2F-2, HER2, MLN19, NEU, NGL, E2F-2
Tested Applications
WB
Protein ID
4758226
Physical Properties
Liquid