N Cadherin (CD325) Antibody

• Background:

  Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density

• NCBI Gene ID:

  1000

• Swiss Prot:

  P19022

• Accession Number:

  NP_001783.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  N-Cadherin (CD325) antibody was raised against a peptide sequence around aa.800~804 (A-I-K-P-V) derived from Human N-Cadherin.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  140 kDa

• Specificity:

  This antibody detects endogenous level of total N-Cadherin protein.

• Applications Notes:

  Western Blot: 1:500

• Symbol:

  CDH2

• NCBI Official Name:

  Cadherin 2, type 1, N-cadherin (neuronal)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bhatt A. S. et. al (2005) Oncogene 24:5333-5343Salomon D. et. al (1992) J. Cell Sci. 102:7-17The MGC Project Team (2004) Genome Res. 14:2121-2127

• Other Product Names:

  CDHN, NCAD, CD325, CDw325, CDH2, CDCN

• Tested Applications:

  WB

• Protein ID:

  14589889

• Physical Properties:

  Liquid