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CD197 Antibody [3D12] (PE)

CAT: 0223-76-932Size: 25 TestsDry Ice: NoHazardous: No
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CAT#:0223-76-932Size:25 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled. It is the receptor for the secondary lymphoid-tissue chemokine (SLC or 6CKine), CCL19, and CCL21. CD197 is expressed on subsets of B and T cells, and mature dendritic cells. The monoclonal 3D12 antibody recognizes the N-terminus of the receptor.
NCBI Gene ID
1236
Swiss Prot
P32248
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
3D12
Conjugation
PE
Type
Primary Antibodies
Field of Research
Immunology, Chemokines & Cytokines, Growth Factors
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgG1, kappa
Specificity
The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled.
Symbol
CCR7
NCBI Official Name
Chemokine (C-C motif) receptor 7
NCBI Organism
Homo sapiens
Background Reference 01
Gattei, V., Godeas, C., Degan, M., Rossi, F. M., Aldinucci, D., Pinto, A. (1999) . Characterization of anti‐CD138 monoclonal antibodies as tools for investigating the molecular polymorphism of syndecan‐1 in human lymphoma cells.British journal of haematology,104 (1), 152-162.
Background Reference 02
Fitzgerald, M. L., Wang, Z., Park, P. W., Murphy, G., Bernfield, M. (2000) . Shedding of syndecan-1 and-4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3sensitive metalloproteinase.The Journal of cell biology,148 (4), 811-824.
Background Reference 03
Itoua Maga, R., Lemieux, J., Roy, A., Simard, C., Nron, S. (2014) . Flow Cytometry Assessment of In Vitro Generated CD138.BioMed research international,2014.
Other Product Names
BLR2, EBI1, CCR-7, CD197, CDw197, CMKBR7, CC-CKR-7, CCR7
Tested Applications
Flow
Physical Properties
Liquid

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