CD29 Antibody [TS2/16] (FITC)

• Background:

  The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells. It forms the VLA- (1-6) molecules with integrin alpha- (1-6) and is involved in the adhesion between cell-cell and cell-matrix. The TS2/16 antibody has been found to activate beta 1 integrins.

• NCBI Gene ID:

  3688

• Swiss Prot:

  P05556

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Clone:

  TS2/16

• Conjugation:

  FITC

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Mouse IgG1, kappa

• Specificity:

  The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells.

• Symbol:

  ITGB1

• NCBI Official Name:

  Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hemler, M. E., Sanchez-Madrid, F., Flotte, T. J., Krensky, A. M., Burakoff, S. J., Bhan, A. K., ... Strominger, J. L. (1984) . Glycoproteins of 210,000 and 130,000 mw on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines.The Journal of Immunology,132 (6), 3011-3018.

• Background Reference 02:

  Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

• Background Reference 03:

  Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., Springer, T. A. (1982) . Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.Proceedings of the National Academy of Sciences,79 (23), 7489-7493.

• Other Product Names:

  CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, ITGB1

• Tested Applications:

  Flow

• Physical Properties:

  Liquid